KaRMa Exotechnologies
KaRMa Exotechnologies
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  • Home
  • About Us
  • Services and Products
  • KaRMa 101 - Preterm Birth
  • KaRMa 102 - Alzheimers
  • KaRMa 103 - Drug delivery

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Our Services and Products

Services

Exosome Engineering & Loading

  • Protein-of-interest packaging (cytokines, enzymes, vaccines, antibodies) 
  • Small molecule loading for enhanced bioavailability
  • CRISPR-based exosome cell line engineering

Targeting & Application

  • Targeting exosomes to specific tissues (reproductive, CNS)
  • Designing & testing client hypotheses

Characterization & Analysis

  • RNA/protein cargo profiling (qPCR, RNA-seq, proteomics)
  • Surface marker profiling (flow cytometry, western blot, NTA) 
  • Uptake & biodistribution studies

GMP Scale-up Consultation

 Expert guidance for Good Manufacturing Practice (GMP) compliant exosome production scale-up 


Products

KaRMa 101 - IL-10-loaded Exosomes

  •  Our lead therapeutic candidate is to prevent preterm birth.
  • Evaluation underway for Endometriosis as well.

KaRMa 102 - Transporter Protein-loaded Exosomes

  •   Exosomes engineered to carry membrane proteins for enhanced cellular uptake.

KaRMa 103 – Targeted Exosome Drug Delivery

  •  Targeted exosome drug delivery vehicles for small molecules using click-chemistry

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